Year: 2016 | Month: April | Volume 6 | Issue 2

Effect of FecB Gene on Body Weight in Black Bengal Goat


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Abstract:

FecB gene is first described gene which has been found to increase ovulation rate and litter size in sheep. But, work related to genetic mechanism and genetic markers for caprine proliferation has not been done so much. The present study was aimed to screen Black Bengal goat population for polymorphism of FecB gene and to study its effect on body weight at different growth stages. DNA samples from 96 animals were isolated and subjected to PCR. Amplified fragments obtained were allowed for polyacrylamide gel electrophoresis for the detection of single strand conformational polymorphism (SSCP) variants. Among all samples, three different SSCP variants were found which were marked as AA, AB and BB. The highest genotype frequency was observed for AB (0.38), which was followed by BB (0.33) and AA (0.29). Least-square analysis of variance showed significant (P<0.01) effect of genotype on body weight at birth only. The least square mean of body weights at birth for genotype BB (01.17±00.03 kg) was significantly lower than that of genotype AA (01.43±00.03 kg) and genotype AB (01.36±00.02 kg). It was also observed that genotype had non-significant effect on body weight at 4-week, 8-week, 12-week, 24-week, 36-week and
48-week of age. These results indicate that effect of FecB on body weight was limited at birth only. No significant effects were found on growth rate at later stage of life. FecB gene was hitherto linked to prolificacy. So, the effect of FecB gene on other traits has important bearing if the research is continued further with more number of species specific primers at other loci.



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