Year: 2022 | Month: April | Volume 12 | Issue 2

Effect of Nano-Nickel Particles on Immune System of Wistar Rats

Jitendra Singh Munish Batra Tushar Gupta Neeraj Kumar
DOI:10.30954/2277-940X.02.2022.1

Abstract:

Nanoparticles that are targeting the immune system is an highly active area of study. Lots of new techniques for immunosuppression depends on nanoparticles as carriers for the delivery of immunosuppressive compounds in small molecules. Efforts have been made to understand mechanisms by which nanoparticles interact directly with the immune system. Nanoparticles immunological activity depends on the physiochemical properties of the nanoparticles and its subsequent internalization inside the body. As the underlying factors for certain reactions are explained, there could be more nanoparticles established and evaluated to cause immunosuppression and to complement immunosuppressive drugs. The current trends and advances in understanding how nanoparticles cause immunosuppressive reactions is still requires more research work in field of nanotechnology.

Highlights

  • Effect of mitogens (CON-A and PHA-M) are well defined on cellular immunity of Wistar Rats.
  • Immuno-suppressive effect of nano-nickel was observed by using various immunological test.


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