Year: 2022 | Month: October | Volume 12 | Issue 5

A Porcine Model to Study the Differential Expression of Myogenic Regulatory Factors (MRFs) in Piglets vis-a-vis Adult Pigs of Indigenous and Large White Yorkshire Breeds

Piyush Kumar Simrinder Singh Sodhi C.S. Mukhopadhyay R.S. Sethi


The pork is considered to be highly nutritious food because it provides many essential nutrients. Pork industry is growing every year because of its high demand across worldwide. In India, pigs rearing can be adapted by weaker section of the farmers because of low investment in it. The Longissimus dorsi muscle is selected from the 12th to 13th rib on the back of pigs. Muscle growth is very important for the production of meat therefore Pax7 and MRFs genes such as MyoD, Myf5 and Myf6 are targeted in the current study to analyse the mRNA transcript level in indigenous and Large White Yorkshire breeds of age one week old piglet and adult respectively. These genes are helpful in muscle regeneration and differentiation. MyoD shows significantly higher (P<0.05) in the indigenous pigs whereas other genes Pax7 and other MRFs i.e., Myf5 and Myf6 shows significant higher (P<0.01) in the LWY breed of both age groups. The current study on differential expression of MRFs in one week old piglets and adult pigs of indigenous and LWY breeds served as candidate markers for muscle growth. This current study may be helpful to know the difference in expression profile in adult and piglet to unravel system biology.


  • We studied Differential expression of myogenic regulatory factors (MRFs) in piglets and adult pigs of indigenous and LWY breeds.
  • The current study helps to understand expression profiling of genes for myogenesis.

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@ Journal of Animal Research | In Association with Association of Mastitis

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