1.Abrol, S., Trehan, A. and Katare, O.P. 2005. Comparative study of different silymarin formulations: formulation, characterization and in vitro/in vivo evaluation. Curr. Drug Deliv., 2: 45-51.

2.Acharya, N.S., Parihar, G.V. and Acharya, S.R. 2011. Phytosomes: Novel approach for delivering herbal extract with improved bioavailability. Int. J. Pharm. Sci., 2(1): 144- 160.

3.Berge, B.V., Swartzendruber, V.A.B. and Geest, J. 1997. Development of an optional protocol for the ultrastructural examination of skin by transmission electron microscopy. J. Microsc., 187: 125-133.

4.Bombardelli, E., Spelta, M., Della, R.L., Sosa, S. and Tubaro, A. 1991. Aging Skin: Protective effect of silymarin- Phytosome. Fitoterapia, 62(2): 115-122.

5.Cevc, G., Schatzlein, A. and Blume, G. 1995. Transdermal drug carriers: basic properties, optimization and transfer efficiency in case of epicutaneously applied peptides. J. Controll. Release, 36: 3-16.

6.Chauhan, N.S., Rajan, G. and Gpoalakrishna, B. 2009. Phytosomes: a potential phytophospholipid carriers for herbal drug delivery. J. Pharm. Res., 2(7): 1267-1270.

7.Comoglio, A., Tomasi, A. and Malandrino, S. 1995. Scavenging effect of silipide-A new silybin phospholipid complex, on ethanol-derived free radicals. Biochem. Pharmacol., 50: 1313-1316.

8.Crema, F., Gatti, G., Barzaghi, N., Pifferi, G. and Perucca, E. 1990. Pharmacokinetic studies on IdB 1016, a silybinphosphatidylcholine complex, in healthy human subjects. Eur. J. Drug Metab. Ph., 15: 333-338.

9.Dayan, N. and Touitou, E. 2002. Carrier for skin delivery of trihexyphenidyl HCL: ethosomesvs liposomes. Biomaterials, 21: 1879-1885.

10.Dhiman, A., Nanda, A. and Ahmad, S. 2012. Novel Herbal Drug Delivery System (NHDDS): the need of hour. Int. Conf. Environ., Chem. Biol., 49: 171-175.

11.Dhiman, A., Nanda, A. and Ahmad, S. 2012. Novel Herbal Drug Delivery System (NHDDS): the need of hour. Int. Conf. Environ., Chem. Biol., 49: 171-175.

12.Filburn, C.R., Kettenacker, R. and Griffin, D.W. 2007. Bioavailability of a silybin-phosphatidylcholine complex in dogs. J. Vet. Pharmacol. Therapeut., 30: 132-138.

13.Fry, D.W., White, J.C. and Goldman, I.D. 1978. Rapid secretion of low molecular weight solutes from liposomes without dilution. Anal. Biochem., 90: 809-815.

14.Gazayerly, O.N., Makhlouf, A.I.A., Soelm, A.M.A. and Mohmoud, M.A. 2013. Antioxidant and Hepatoprotective effects of silymarin phytosomes compared to milk thistle extract in carbon tetrachloride induced hepatotoxicity in rats. J. Microencapsul., 2: 1-8.

15.Jain, N.K. 2005. Controlled and Novel drug delivery, CBS publisher & Distributors, Ist Edn, pp. 321-326.

16.Kidd, P.M. 2002. Phosphatidylcholine, An Alternative Medicine Review Monograph. Thorne Res., 1: 310-315.

17.Kumar, A.B., Habbu, P., Thimmasetty, Lakshman, Hullatti, P. and Kumar, S.R. 2017. Phytosomes as Novel Drug Delivery system for Herbal medicine- A Review. Sys. Rev. Pharm., 8(1): 5-7.

18.Maghraby, G.M.M., Williams, A.C. and Barry, B.W. 2000. Oestradiol skin delivery from ultradeformable liposomes: refinement of surfactant concentration. Int. J. Pharm., 196: 63-74.

19.Maiti, K., Mukherjee, K., Gantait, A., Ahmed, H.N., Saha, B.P. and Mukherjee, P.K. 2005. Enhanced therapeutic benefit of quercetin- phospholipid complex in carbon tetrachlorideinduced acute liver injury in rats: a comparative study. Iranian J. Pharmacol. Therapeut., 4(2): 84-90.

20.Maiti, K., Mukherjee, K., Gantait, A., Saha, B.P. and Mukherjee, P.K. 2007. Curcumin-phospholipid complex: preparation, therapeutic evaluation and pharmacokinetic study in rats. Int. J. Pharm., 330: 155-163.

21.Mascarella, S. 1993. Therapeutic & anti lipoperoxidant effects of silybin- phosphatidylcholine complex in chronic liver disease. Curr. Therapeu. Res., 53: 98-102.

22.Patel, J., Patel, R., Kapil, K. and Patel, N. 2009. An overview of phytosomes as an advanced herbal drug delivery system. Asian J. Pharmaceu. Sci., 4(6): 363-371.

23.Priyanka, M.K., Saluja, S. and Rachana. 2011. Phytosomes. The Pharma. Rev., 2: 99-113.

24.Raju, T.P., Reddy, M.S. and Reddy, V.P. 2011. Phytosomes: A novel phytophospholipid carriers for herbal drug delivery. Int. Res. J. Pharm., 2(6): 28-33.

25.Saha, S., Sarma, A., Saikia, P. and Chakrabarty, T. 2013. Phytosome: A Brief Overview. Scholars Acad. J. Pharm., 2(1): 12-20.

26.Semalty, A., Semalty, M. and Rawat, M.S.M. 2007. The phytophospholipid complexes- phytosomes: a potential therapeutic approach for herbal hepatoprotective drug delivery. Pharmacogn. Rev., 1: 369-374.

27.Semalty, A., Semalty, R., Singh, R. and Rawat, M.S.M. 2006. Phytosomes in herbal drug delivery. Indian Drugs, 43: 937- 946.

28.Sharma, S. and Roy, R.K. 2010. Phytosomes : An emerging technology. Int. J. Pharmaceu. Res. Dev., 2(5): 1-7.

29.Sikarwar, M.S., Sharma, S., Amit, J.K. and Parial, S.D. 2008. Preparation, characterization and evaluation of Marsupsinphospholipid complex. Am. Assoc. Pharmaceu. Sci., 9: 129- 137.

30.Singh, R.P., Parpani, S., Narke, R. and Chavan, R. 2014. Phytosomes: Recent advance research for novel drug delivery system. Asian J. Pharmaceu. Res. Dev., 2(3): 15-29.

31.Swati, R. and Sapna, M. 2012. Phytosomal drug delivery systems. Int. J. Res. Dev. Pharm. Life Sci., 1(3): 143-150.

32.Yanyu, X., Yunmei, S. and Zhipeng, C. 2006. The preparation of silybin-phospholipid complex and the study on its pharmacokinetics in rats. Int. J. Pharm., 307: 77-82.