The present study was conducted to evaluate the clinical outcome of intraocular silicone prosthesis implantation in dogs with irreparable traumatic and chronic ocular conditions. During November 2025 to April 2026, 4,921 canine cases presented at the Veterinary Clinical Complex, College of Veterinary Science, Jabalpur, were screened, of which 262 (5.32%) had ocular affections and 16 (0.33%) had irreparable ocular conditions. Twelve dogs were selected for surgical management irrespective of age, breed and sex. Preoperative clinical, ophthalmic, ultrasonographic and haemato-biochemical evaluations were performed. Implant size was determined from the axial globe length of the contralateral normal eye (axial globe length - 3 mm). Four dogs with closed globe injuries underwent perilimbal evisceration, whereas eight dogs with open globe injuries were managed by the four-petal evisceration technique followed by intraocular silicone prosthesis implantation; extraocular prosthesis was placed after complete conjunctival healing. Traumatic injury was the predominant cause (68.75%), with adult male non-descript dogs being most commonly affected. Mean axial globe length and implant size were 17.94 ± 0.51 mm and 14.66 ± 0.51 mm, respectively. Postoperative pain and eyelid swelling resolved completely by day 15 and day 10, respectively, while ocular discharge persisted in only one dog. Functional and cosmetic appearance was graded as excellent in 75% and good in 25% of dogs. No intraocular implant failure was observed during the 60-day follow-up, although one extraocular prosthesis was dislodged. The study demonstrated that intraocular silicone prosthesis implantation, particularly when combined with the four-petal evisceration technique and an extraocular prosthesis, is an effective option for restoring cosmetic appearance and maintaining satisfactory eyelid function in dogs with irreparable ocular conditions.